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Angiotensin II receptor type 1 or AT 1
receptor is the best characterized
angiotensin receptor.It has vasopressor effects and regulates aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system.
Angiotensin II receptor antagonists are drugs indicated for hypertension, diabetic nephropathy and congestive heart failure
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angiotensin converting enzyme (ACE) inhibitors and
angiotensin receptor blockers (ARBs) are used widely to treat hypertension, with ARBs often substituted for ACE inhibitors due to a reputation of having fewer side ...
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angiotensin II receptors, (AGTR1) and (AGTR2), are a class of G protein-coupled receptors with
angiotensin II as their ligands. They are important in the renin–
angiotensin system: they are responsible for the signal transduction of the vasoconstricting stimulus of the main effector hormone,
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angiotensin converting enzyme (ACE) inhibitors and are used for the same indications (hypertension, heart failure, post- myocardial infarction).Their mechanism of action, however, is very different from ACE inhibitors, which inhibit the formation of
angiotensin II.
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Angiotensin receptor blockers (also called ARBs or
angiotensin II inhibitors) are medicines that dilate (widen) blood vessels, and are used in the treatment of conditions such as high blood pressure (hypertension), heart failure, or kidney disease in people with diabetes.. ARBs work by blocking the action of a natural chemical called
angiotensin II.
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