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5.
Role of mitochondria in
autophagy. Mitochondria and their physical dynamics play a vital
role at several stages of
autophagy from initial biogenesis of autophagosome and regulation of the
autophagy through beclin-1 to the
autophagy-mediated cell death (Rubinsztein et al., 2012).Recent studies show that the mitochondrial outer membrane recruits the
autophagy proteins ATG5 and LC3.
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