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1. Introduction.
Bone morphogenic protein-2 (BMP-2) is one of the most potent osteoinductive molecules from the BMP family and can induce
bone at both entopic and ectopic locations , , .The biological half-life of commercially available BMPs is very short (< 12h) , and the development of carrier materials for site specific delivery may enhance the bioactivity of BMP in-vivo. Bone Cold (Bone Series) download 1. Introduction.
Bone metastases are particularly common in patients with breast, prostate, and lung cancer. In a
bone metastasis, tumor cells transferred to the
bone adhere to marrow stromal cells via cell adhesion molecules and several growth factors such as parathyroid hormone-related protein-C, prostaglandin E2, interleukin (IL)-6, IL-8, and IL-11.
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bone spur is an outgrowth of
bone that can occur along the edges of a
bone. It is also called an osteophyte.
Bone spurs can form in any
bone but are most commonly found in joints, where two or more bones come together.
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