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Type VI CRISPR systems, including the enzymes Cas13a/C2c2 and Cas13b, target RNA rather than DNA. Fusing an ADAR2(E488Q) adenosine deaminase to catalytically dead Cas13b creates a programmable RNA base editor that converts adenosine to inosine in RNA (termed REPAIR.) Since inosine is functionally equivalent to guanosine, the result is an A->G change in RNA. dPspCas13b … Frøken Ingenting Buckling and Postbuckling of Composite Plates Much fascinating and valuable research has been devoted to the molecular biology of the eye, its various structures, and its innervation this past decade. Domenico Ghirlandaio: 110 Renaissance Paintings