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7/7/2001 · Introduction. Ion channels are key molecules for signal transduction across biological membranes. Combining physiological experiments with DNA sequence data has recently linked many diseases to defects in ion channels and, to acknowledge this, the …
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The Time Machine: Large Print Edition Redressement Et Liquidation Judiciaires Loss-of-function mutations in ion channels often lead to recessive disease, as is the case with CFTR mutations in cystic fibrosis or with CLCNKB mutations in Bartter syndrome (2,3). However, as many ion channels are multimeric complexes, certain loss-of-function mutations may …
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