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mitochondrial function and the accumulation of abnormal mitochondria. However, the precise mechanisms by which aging promotes these
mitochondrial alterations and the role of the latter in aging are still not fully understood.
Mitochondrial dynamics is a key process regulating
mitochondrial function and quality.
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mitochondrial proteins are encoded by nuclear genes, translated in the cytoplasm and then imported into mitochondria ().
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Mitochondrial biogenesis is the process by which cells increase
mitochondrial mass. It was first described by John Holloszy in the 1960s, when it was discovered that physical endurance training induced higher
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