Malfolded proteins in the endoplasmic reticulum (ER) inhibit
translation initiation. This response is likely mediated by increased phosphorylation of eIF2-alpha and is thought to reduce the workload imposed on the folding machinery during stress. Recent Examples on the Web. The transformation marks Hathaway’s
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Initiation Factor 2 (
eIF2) is a eukaryotic
initiation factor.It is required for most forms of eukaryotic
translation initiation.
eIF2 mediates the binding of tRNA i Met to the ribosome in a GTP-dependent manner.
eIF2 is a heterotrimer consisting of an alpha (also called subunit 1), a beta (subunit 2), and a gamma (subunit 3) subunit.. Once the
initiation phase has completed,
eIF2 is ...
Death Blow BioCoach Activity Concept 11:
Initiation of
Translation. An
initiation complex for
translation forms by the assembly of the ribosomal subunits and initiator tRNA (met-tRNA) at the start codon on the mRNA.
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Translation is the RNA directed synthesis of polypeptides. This process requires all three classes of RNA. Although the chemistry of peptide bond formation is relatively simple, the processes leading to the ability to form a peptide bond are exceedingly complex.
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Initiation Protocol (SIP) ist ein Netzprotokoll zum Aufbau, zur Steuerung und zum Abbau einer Kommunikationssitzung zwischen zwei und mehr Teilnehmern. Das Protokoll wird u. a. im RFC 3261 spezifiziert. In der IP-Telefonie ist das SIP ein häufig angewandtes Protokoll.
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