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Microfluidic cell culture has significant advantages over macroscopic culture, that is, culture in flasks, dishes and well-plates. Fig. 1 describes the most significant advantages and challenges when using macroscopic versus
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lab-on-a-chip (LOC) is a device that integrates one or several laboratory functions on a single integrated circuit (commonly called a "chip") of only millimeters to a few square centimeters to achieve automation and high-throughput screening. LOCs can handle extremely small fluid volumes down to less than pico-liters.
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systems (MEMS ... download Microfluidic devices and systems android Complex biological organisms can be viewed as hierarchical ensembles of cooperating units with controlling elements that operate at the micro & nanoscale.
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