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Positron emission tomography with (18F)2-fluoro-2-deoxy-D-glucose (PET-FDG) is an imaging metabolic technique. PET-FDG is more precise than CT for the evaluation of mediastinal affectation of patients with non-small cell lung cancer, offering a high negative predictive value. PET-CT systems were initially proposed by David Townsend (at the University of Geneva at the time) and Ronald Nutt (at CPS Innovations in Knoxville, TN) with help from colleagues. The first PET-CT prototype for clinical evaluation was funded by the NCI and installed at the University of Pittsburgh Medical Center in 1998. The first commercial system reached the market by 2001, and by 2004, over ... 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