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Spinal and bulbar muscular atrophy (SBMA), popularly known as Kennedy's disease, is a progressive debilitating neurodegenerative disorder resulting in muscle cramps and progressive weakness due to degeneration of motor neurons in the brainstem and spinal cord.. The condition is associated with mutation of the androgen receptor (AR) gene and is inherited in an X-linked recessive manner. Please select whether you prefer to
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11/19/2018 ·
Multiple or bilateral renal carcinomas have been reported in association with this
syndrome, most commonly hybrid oncocytic tumors with features of chromophobe renal carcinoma (50%), followed by chromophobe renal cancer, clear cell renal carcinoma, and renal oncocytoma.
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Osteopontin (OPN), also known as bone sialoprotein I (BSP-1 or BNSP), early T-lymphocyte activation (ETA-1), secreted phosphoprotein 1 (SPP1), 2ar and Rickettsia resistance (Ric), is a protein that in humans is encoded by the SPP1 gene (secreted phosphoprotein 1). The murine ortholog is Spp1.
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Advances in anti-aging medicine IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response.
Dirk Brenner, Luxembourg Institute of Health, Infection & Immunity, Faculty Member. Studies Human Sciences, Immune response, and Sepsis.
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