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Prayers for Impossible Days Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders.. The exact mechanism of action of SSRIs is unknown.: 20 SSRIs are believed to increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption (reuptake) into the presynaptic cell ... The Creative Writer: Level One: Five Finger Exercises (The Creative... Learn about the different types of antidepressants such as TCAs, SSRIs, and MAOIs. Side effects, drug interactions, and conditions antidepressants are prescribed is included in the information. 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